Analysis of Changes in Brain Region and Connectomics in the Acute Stage of Sudden Sensorineural Hearing Loss in the Resting State via Functional Magnetic Resonance Imaging

To explore the functional changes in whole brain network patients with sudden sensorineural hearing loss (SHL) at acute stage from magnetic resonance imaging (fMRI) evaluation results, 80 right SHL were selected as subjects (patient group). In addition, 40 healthy volunteers who underwent physical examination hospital during same period recruited a control group. fMRI was performed to analyze parameters and core nodes of network. It found that all thresholds, Cp Lp patient group dramatically superior those The parameter Eglobal substantially lower than ( P < 0.05 ). At most λ id="M2"> There ten specific patients, including parahippocampal gyrus, supra-occipital left suboccipital fusiform parietal lobule, subparietal temporal marginal gyrus. summary, brains still had small-world attributes, but some characteristics changed, there trend transformation regular connection between auditory area areas related language vision weakened, distribution changed. This study provides reference basis for exploring local connectome levels phase based on resting-state fMRI.